Bacterial secretion of soluble and functional trivalent scFv-based N-terminal trimerbodies

Recombinant antibodies are used with great success in many different diagnostic and therapeutic applications. A variety of protein expression systems are available, but nowadays almost all therapeutic antibodies are produced in mammalian cell lines due to their complex structure and glycosylation re...

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Detalles Bibliográficos
Autores principales: Blanco-Toribio, Ana, Álvarez-Cienfuegos, Ana, Sainz-Pastor, Noelia, Merino, Nekane, Compte, Marta, Sanz, Laura, Blanco, Francisco J, Álvarez-Vallina, Luis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523561/
https://www.ncbi.nlm.nih.gov/pubmed/26239030
http://dx.doi.org/10.1186/s13568-015-0137-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523561/
https://www.ncbi.nlm.nih.gov/pubmed/26239030
http://dx.doi.org/10.1186/s13568-015-0137-0

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