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Bacterial secretion of soluble and functional trivalent scFv-based N-terminal trimerbodies
Recombinant antibodies are used with great success in many different diagnostic and therapeutic applications. A variety of protein expression systems are available, but nowadays almost all therapeutic antibodies are produced in mammalian cell lines due to their complex structure and glycosylation re...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523561/ https://www.ncbi.nlm.nih.gov/pubmed/26239030 http://dx.doi.org/10.1186/s13568-015-0137-0 |