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Rapid pairing and resegregation of distant homologous loci enables double-strand break repair in bacteria

Double-strand breaks (DSBs) can lead to the loss of genetic information and cell death. Although DSB repair via homologous recombination has been well characterized, the spatial organization of this process inside cells remains poorly understood, and the mechanisms used for chromosome resegregation...

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Detalles Bibliográficos
Autores principales: Badrinarayanan, Anjana, Le, Tung B.K., Laub, Michael T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523614/
https://www.ncbi.nlm.nih.gov/pubmed/26240183
http://dx.doi.org/10.1083/jcb.201505019