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Expression Profile of Sonic Hedgehog Pathway Members in the Developing Human Fetal Brain

The Sonic Hedgehog (SHH) pathway plays a central role in the developing mammalian CNS. In our study, we aimed to investigate the spatiotemporal SHH pathway expression pattern in human fetal brains. We analyzed 22 normal fetal brains for Shh, Patched, Smoothened, and Gli1-3 expression by immunohistoc...

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Detalles Bibliográficos
Autores principales: Tichy, Julia, Zinke, Jenny, Bunz, Benedikt, Meyermann, Richard, Harter, Patrick N., Mittelbronn, Michel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523658/
https://www.ncbi.nlm.nih.gov/pubmed/26266257
http://dx.doi.org/10.1155/2015/494269