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A Conserved Circular Network of Coregulated Lipids Modulates Innate Immune Responses

Lipid composition affects the biophysical properties of membranes that provide a platform for receptor-mediated cellular signaling. To study the regulatory role of membrane lipid composition, we combined genetic perturbations of sphingolipid metabolism with the quantification of diverse steps in Tol...

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Detalles Bibliográficos
Autores principales: Köberlin, Marielle S., Snijder, Berend, Heinz, Leonhard X., Baumann, Christoph L., Fauster, Astrid, Vladimer, Gregory I., Gavin, Anne-Claude, Superti-Furga, Giulio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cell Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523684/
https://www.ncbi.nlm.nih.gov/pubmed/26095250
http://dx.doi.org/10.1016/j.cell.2015.05.051