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The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosis

Although efforts to identify novel therapies for the treatment of tuberculosis have led to the identification of several promising drug candidates, the identification of high-quality hits from conventional whole-cell screens remains disappointingly low. The elucidation of the genome sequence of Myco...

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Detalles Bibliográficos
Autores principales: Evans, Joanna C., Mizrahi, Valerie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523840/
https://www.ncbi.nlm.nih.gov/pubmed/26300875
http://dx.doi.org/10.3389/fmicb.2015.00812