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A Systems Level Analysis of Vasopressin-mediated Signaling Networks in Kidney Distal Convoluted Tubule Cells

The kidney distal convoluted tubule (DCT) plays an essential role in maintaining body sodium balance and blood pressure. The major sodium reabsorption pathway in the DCT is the thiazide-sensitive NaCl cotransporter (NCC), whose functions can be modulated by the hormone vasopressin (VP) acting via un...

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Detalles Bibliográficos
Autores principales: Cheng, Lei, Wu, Qi, Kortenoeven, Marleen L. A., Pisitkun, Trairak, Fenton, Robert A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523861/
https://www.ncbi.nlm.nih.gov/pubmed/26239621
http://dx.doi.org/10.1038/srep12829