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Contacts-based prediction of binding affinity in protein–protein complexes

Almost all critical functions in cells rely on specific protein–protein interactions. Understanding these is therefore crucial in the investigation of biological systems. Despite all past efforts, we still lack a thorough understanding of the energetics of association of proteins. Here, we introduce...

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Detalles Bibliográficos
Autores principales: Vangone, Anna, Bonvin, Alexandre MJJ
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523921/
https://www.ncbi.nlm.nih.gov/pubmed/26193119
http://dx.doi.org/10.7554/eLife.07454