HAUSP-nucleolin interaction is regulated by p53-Mdm2 complex in response to DNA damage response

HAUSP (herpes virus-associated ubiquitin specific protease, known as ubiquitin specific protease 7), one of DUBs, regulates the dynamics of the p53 and Mdm2 network in response to DNA damage by deubiquitinating both p53 and its E3 ubiquitin ligase, Mdm2. Its concerted action increases the level of f...

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Detalles Bibliográficos
Autores principales: Lim, Key-Hwan, Park, Jang-Joon, Gu, Bon-Hee, Kim, Jin-Ock, Park, Sang Gyu, Baek, Kwang-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523935/
https://www.ncbi.nlm.nih.gov/pubmed/26238070
http://dx.doi.org/10.1038/srep12793

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523935/
https://www.ncbi.nlm.nih.gov/pubmed/26238070
http://dx.doi.org/10.1038/srep12793

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