IRF6 is the mediator of TGFβ3 during regulation of the epithelial mesenchymal transition and palatal fusion

Mutation in interferon regulatory factor 6 (IRF6) is known to cause syndromic and non-syndromic cleft lip/palate in human. In this study, we investigated the molecular mechanisms related to IRF6 during palatal fusion using palatal shelves organ culture. The results showed that ablation of Irf6 resul...

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Detalles Bibliográficos
Autores principales: Ke, Chen-Yeh, Xiao, Wen-Lin, Chen, Chun-Ming, Lo, Lun-Jou, Wong, Fen-Hwa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523936/
https://www.ncbi.nlm.nih.gov/pubmed/26240017
http://dx.doi.org/10.1038/srep12791

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523936/
https://www.ncbi.nlm.nih.gov/pubmed/26240017
http://dx.doi.org/10.1038/srep12791

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