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IRF6 is the mediator of TGFβ3 during regulation of the epithelial mesenchymal transition and palatal fusion
Mutation in interferon regulatory factor 6 (IRF6) is known to cause syndromic and non-syndromic cleft lip/palate in human. In this study, we investigated the molecular mechanisms related to IRF6 during palatal fusion using palatal shelves organ culture. The results showed that ablation of Irf6 resul...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523936/ https://www.ncbi.nlm.nih.gov/pubmed/26240017 http://dx.doi.org/10.1038/srep12791 |