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Genomic prediction of celiac disease targeting HLA-positive individuals

BACKGROUND: Genomic prediction aims to leverage genome-wide genetic data towards better disease diagnostics and risk scores. We have previously published a genomic risk score (GRS) for celiac disease (CD), a common and highly heritable autoimmune disease, which differentiates between CD cases and po...

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Detalles Bibliográficos
Autores principales: Abraham, Gad, Rohmer, Alexia, Tye-Din, Jason A., Inouye, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523954/
https://www.ncbi.nlm.nih.gov/pubmed/26244058
http://dx.doi.org/10.1186/s13073-015-0196-5