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Importance of presenting the variability of the false discovery rate control

BACKGROUND: Multiple hypothesis testing is a pervasive problem in genomic data analysis. The conventional Bonferroni method which controls the family-wise error rate is conservative and with low power. The current paradigm is to control the false discovery rate. RESULTS: We characterize the variabil...

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Detalles Bibliográficos
Autores principales: Lin, Yi-Ting, Lee, Wen-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4523994/
https://www.ncbi.nlm.nih.gov/pubmed/26239642
http://dx.doi.org/10.1186/s12863-015-0259-z