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CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases

Animal models are extremely valuable to help us understand the pathogenesis of neurodegenerative disorders and to find treatments for them. Since large animals are more like humans than rodents, they make good models to identify the important pathological events that may be seen in humans but not in...

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Detalles Bibliográficos
Autores principales: Tu, Zhuchi, Yang, Weili, Yan, Sen, Guo, Xiangyu, Li, Xiao-Jiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524001/
https://www.ncbi.nlm.nih.gov/pubmed/26238861
http://dx.doi.org/10.1186/s13024-015-0031-x