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CRISPR/Cas9: a powerful genetic engineering tool for establishing large animal models of neurodegenerative diseases
Animal models are extremely valuable to help us understand the pathogenesis of neurodegenerative disorders and to find treatments for them. Since large animals are more like humans than rodents, they make good models to identify the important pathological events that may be seen in humans but not in...
Autores principales: | Tu, Zhuchi, Yang, Weili, Yan, Sen, Guo, Xiangyu, Li, Xiao-Jiang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524001/ https://www.ncbi.nlm.nih.gov/pubmed/26238861 http://dx.doi.org/10.1186/s13024-015-0031-x |
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