Niosomal carriers enhance oral bioavailability of carvedilol: effects of bile salt-enriched vesicles and carrier surface charge

Carvedilol (CRV) is an antihypertensive drug with both alpha and beta receptor blocking activity used to preclude angina and cardiac arrhythmias. To overcome the low, variable oral bioavailability of CRV, niosomal formulations were prepared and characterized: plain niosomes (without bile salts), bil...

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Detalles Bibliográficos
Autores principales: Arzani, Gelareh, Haeri, Azadeh, Daeihamed, Marjan, Bakhtiari-Kaboutaraki, Hamid, Dadashzadeh, Simin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524462/
https://www.ncbi.nlm.nih.gov/pubmed/26251598
http://dx.doi.org/10.2147/IJN.S84703

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524462/
https://www.ncbi.nlm.nih.gov/pubmed/26251598
http://dx.doi.org/10.2147/IJN.S84703

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