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Partial Loss of Genomic Imprinting Reveals Important Roles for Kcnq1 and Peg10 Imprinted Domains in Placental Development

Mutations in imprinted genes or their imprint control regions (ICRs) produce changes in imprinted gene expression and distinct abnormalities in placental structure, indicating the importance of genomic imprinting to placental development. We have recently shown that a very broad spectrum of placenta...

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Detalles Bibliográficos
Autores principales: Koppes, Erik, Himes, Katherine P., Chaillet, J. Richard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524636/
https://www.ncbi.nlm.nih.gov/pubmed/26241757
http://dx.doi.org/10.1371/journal.pone.0135202