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Lopinavir/Ritonavir Impairs Physical Strength in Association with Reduced Igf1 Expression in Skeletal Muscle of Older Mice

BACKGROUND: Late-middle age HIV patients are prone to fatigue despite effective viral control by antiretroviral therapies. Rodent models to recapitulate this phenotype are still not available. HYPOTHESIS: Drug treatment may compromise muscle strength and physical performance more in older individual...

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Detalles Bibliográficos
Autores principales: Wong, Siu, Bhasin, Shalender, Serra, Carlo, Yu, Yanan, Deng, Lynn, Guo, Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524660/
https://www.ncbi.nlm.nih.gov/pubmed/26251758
http://dx.doi.org/10.4172/2155-6113.1000216