Differential Effects of Dabigatran and Warfarin on Bone Volume and Structure in Rats with Normal Renal Function

BACKGROUND: Warfarin, a widely used anticoagulant, is a vitamin K antagonist impairing the activity of vitamin K-dependent Bone Gla Protein (BGP or Osteocalcin) and Matrix Gla Protein (MGP). Because dabigatran, a new anticoagulant, has no effect on vitamin K metabolism, the aim of this study was to...

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Detalles Bibliográficos
Autores principales: Fusaro, Maria, Dalle Carbonare, Luca, Dusso, Adriana, Arcidiacono, Maria Vittoria, Valenti, Maria Teresa, Aghi, Andrea, Pasho, Sabina, Gallieni, Maurizio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524674/
https://www.ncbi.nlm.nih.gov/pubmed/26241483
http://dx.doi.org/10.1371/journal.pone.0133847

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524674/
https://www.ncbi.nlm.nih.gov/pubmed/26241483
http://dx.doi.org/10.1371/journal.pone.0133847

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