Structure and Function in Homodimeric Enzymes: Simulations of Cooperative and Independent Functional Motions

Large-scale conformational change is a common feature in the catalytic cycles of enzymes. Many enzymes function as homodimers with active sites that contain elements from both chains. Symmetric and anti-symmetric cooperative motions in homodimers can potentially lead to correlated active site openin...

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Detalles Bibliográficos
Autores principales: Wells, Stephen A., van der Kamp, Marc W., McGeagh, John D., Mulholland, Adrian J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524684/
https://www.ncbi.nlm.nih.gov/pubmed/26241964
http://dx.doi.org/10.1371/journal.pone.0133372

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524684/
https://www.ncbi.nlm.nih.gov/pubmed/26241964
http://dx.doi.org/10.1371/journal.pone.0133372

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