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Structure and Function in Homodimeric Enzymes: Simulations of Cooperative and Independent Functional Motions
Large-scale conformational change is a common feature in the catalytic cycles of enzymes. Many enzymes function as homodimers with active sites that contain elements from both chains. Symmetric and anti-symmetric cooperative motions in homodimers can potentially lead to correlated active site openin...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524684/ https://www.ncbi.nlm.nih.gov/pubmed/26241964 http://dx.doi.org/10.1371/journal.pone.0133372 |