Computational Structure-Based De Novo Design of Hypothetical Inhibitors against the Anti- Inflammatory Target COX-2

Cyclooxygenase-2 (COX-2) produces prostaglandins in inflamed tissues and hence has been considered as an important target for the development of anti-inflammatory drugs since long. Administration of traditional non-steroidal anti-inflammatory drugs (NSAIDs) and other COX-2 selective inhibitors (COXI...

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Detalles Bibliográficos
Autores principales: Dhanjal, Jaspreet Kaur, Sreenidhi, Anith Kumar, Bafna, Khushboo, Katiyar, Shashank Prakash, Goyal, Sukriti, Grover, Abhinav, Sundar, Durai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524694/
https://www.ncbi.nlm.nih.gov/pubmed/26241744
http://dx.doi.org/10.1371/journal.pone.0134691

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524694/
https://www.ncbi.nlm.nih.gov/pubmed/26241744
http://dx.doi.org/10.1371/journal.pone.0134691

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