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mTORC1 Prevents Preosteoblast Differentiation through the Notch Signaling Pathway

The mechanistic target of rapamycin (mTOR) integrates both intracellular and extracellular signals to regulate cell growth and metabolism. However, the role of mTOR signaling in osteoblast differentiation and bone formation is undefined, and the underlying mechanisms have not been elucidated. Here,...

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Detalles Bibliográficos
Autores principales: Huang, Bin, Wang, Yongkui, Wang, Wenhao, Chen, Juan, Lai, Pinglin, Liu, Zhongyu, Yan, Bo, Xu, Song, Zhang, Zhongmin, Zeng, Chun, Rong, Limin, Liu, Bin, Cai, Daozhang, Jin, Dadi, Bai, Xiaochun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4524707/
https://www.ncbi.nlm.nih.gov/pubmed/26241748
http://dx.doi.org/10.1371/journal.pgen.1005426