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Chemosensitization of multidrug resistant Candida albicans by the oxathiolone fused chalcone derivatives

Three structurally related oxathiolone fused chalcone derivatives appeared effective chemosensitizers, able to restore in part sensitivity to fluconazole of multidrug-resistant C. albicans strains. Compound 21 effectively chemosensitized cells resistant due to the overexpression of the MDR1 gene, co...

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Detalles Bibliográficos
Autores principales: Ła̧cka, Izabela, Konieczny, Marek T., Bułakowska, Anita, Kodedová, Marie, Gašková, Dana, Maurya, Indresh K., Prasad, Rajendra, Milewski, Sławomir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525051/
https://www.ncbi.nlm.nih.gov/pubmed/26300857
http://dx.doi.org/10.3389/fmicb.2015.00783