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Chemosensitization of multidrug resistant Candida albicans by the oxathiolone fused chalcone derivatives
Three structurally related oxathiolone fused chalcone derivatives appeared effective chemosensitizers, able to restore in part sensitivity to fluconazole of multidrug-resistant C. albicans strains. Compound 21 effectively chemosensitized cells resistant due to the overexpression of the MDR1 gene, co...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2015
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525051/ https://www.ncbi.nlm.nih.gov/pubmed/26300857 http://dx.doi.org/10.3389/fmicb.2015.00783 |