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Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation

Chromosome condensation is a hallmark of mitosis in eukaryotes and is a prerequisite for faithful segregation of genetic material to daughter cells. Here we show that condensin, which is essential for assembling condensed chromosomes, helps to preclude the detrimental effects of gene transcription o...

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Detalles Bibliográficos
Autores principales: Sutani, Takashi, Sakata, Toyonori, Nakato, Ryuichiro, Masuda, Koji, Ishibashi, Mai, Yamashita, Daisuke, Suzuki, Yutaka, Hirano, Tatsuya, Bando, Masashige, Shirahige, Katsuhiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525155/
https://www.ncbi.nlm.nih.gov/pubmed/26204128
http://dx.doi.org/10.1038/ncomms8815