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Condensin targets and reduces unwound DNA structures associated with transcription in mitotic chromosome condensation
Chromosome condensation is a hallmark of mitosis in eukaryotes and is a prerequisite for faithful segregation of genetic material to daughter cells. Here we show that condensin, which is essential for assembling condensed chromosomes, helps to preclude the detrimental effects of gene transcription o...
Autores principales: | Sutani, Takashi, Sakata, Toyonori, Nakato, Ryuichiro, Masuda, Koji, Ishibashi, Mai, Yamashita, Daisuke, Suzuki, Yutaka, Hirano, Tatsuya, Bando, Masashige, Shirahige, Katsuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Pub. Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525155/ https://www.ncbi.nlm.nih.gov/pubmed/26204128 http://dx.doi.org/10.1038/ncomms8815 |
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