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Infrared nanospectroscopy characterization of oligomeric and fibrillar aggregates during amyloid formation

Amyloids are insoluble protein fibrillar aggregates. The importance of characterizing their aggregation has steadily increased because of their link to human diseases and material science applications. In particular, misfolding and aggregation of the Josephin domain of ataxin-3 is implicated in spin...

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Detalles Bibliográficos
Autores principales: Ruggeri, F. S., Longo, G., Faggiano, S., Lipiec, E., Pastore, A., Dietler, G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525161/
https://www.ncbi.nlm.nih.gov/pubmed/26215704
http://dx.doi.org/10.1038/ncomms8831