Reformulating Tylocrebrine in Epidermal Growth Factor Receptor Targeted Polymeric Nanoparticles Improves Its Therapeutic Index

[Image: see text] Several promising anticancer drug candidates have been sidelined owing to their poor physicochemical properties or unfavorable pharmacokinetics, resulting in high overall cost of drug discovery and development. Use of alternative formulation strategies that alleviate these issues c...

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Detalles Bibliográficos
Autores principales: Kirtane, Ameya R., Wong, Henry L., Guru, Bharath Raja, Lis, Lev G., Georg, Gunda I., Gurvich, Vadim J., Panyam, Jayanth
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2015
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525301/
https://www.ncbi.nlm.nih.gov/pubmed/26065924
http://dx.doi.org/10.1021/acs.molpharmaceut.5b00173

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525301/
https://www.ncbi.nlm.nih.gov/pubmed/26065924
http://dx.doi.org/10.1021/acs.molpharmaceut.5b00173

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