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Reduced Expression of Argonaute 1, Argonaute 2, and TRBP Changes Levels and Intracellular Distribution of RNAi Factors

Until recently, Argonaute 2 (AGO2) and other RNA factors were believed to be restricted to the cytoplasm of mammalian somatic cells. It is now becoming appreciated that RNAi factors can also be found in cell nuclei, but much remains to be learned about their transport, molecular recognition, and fun...

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Detalles Bibliográficos
Autores principales: Matsui, Masayuki, Li, Liande, Janowski, Bethany A., Corey, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525381/
https://www.ncbi.nlm.nih.gov/pubmed/26242502
http://dx.doi.org/10.1038/srep12855