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Binding of the eukaryotic translation elongation factor 1A with the 5’UTR of HIV-1 genomic RNA is important for reverse transcription

BACKGROUND: The cellular protein eukaryotic translation elongation factor 1A (eEF1A) binds to aminoacylated transfer RNAs and delivers them to the ribosome during translation. eEF1A also binds to RNA secondary structures present in genomes of several RNA viruses and plays important roles in their re...

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Detalles Bibliográficos
Autores principales: Li, Dongsheng, Wei, Ting, Jin, Hongping, Rose, Amanda, Wang, Rui, Lin, Min-Hsuan, Spann, Kirsten, Harrich, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525723/
https://www.ncbi.nlm.nih.gov/pubmed/26242867
http://dx.doi.org/10.1186/s12985-015-0337-x