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Tumor-associated macrophages in oral premalignant lesions coexpress CD163 and STAT1 in a Th1-dominated microenvironment

BACKGROUND: Tumor-associated macrophages (TAMs) are implicated in the growth, invasion and metastasis of various solid tumors. However, the phenotype of TAMs in premalignant lesions of solid tumors has not been clarified. In the present study, we identify the phenotype of TAMs in leukoplakia, an ora...

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Detalles Bibliográficos
Autores principales: Mori, Kazumasa, Haraguchi, Shigeki, Hiori, Miki, Shimada, Jun, Ohmori, Yoshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525742/
https://www.ncbi.nlm.nih.gov/pubmed/26242181
http://dx.doi.org/10.1186/s12885-015-1587-0