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High Skp2/Low p57(Kip2) Expression is Associated with Poor Prognosis in Human Breast Carcinoma

Downregulation of p57(Kip2) is involved in tumor progression, and S-phase kinase-associated protein 2 (Skp2) is an E3 ligase that regulates a variety of cell cycle proteins. However, the prognostic value of p57(Kip2) and its correlation with Skp2 in breast cancer have not been fully elucidated. Here...

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Detalles Bibliográficos
Autores principales: Yang, Chengcheng, Nan, Haocheng, Ma, Jiequn, Jiang, Lili, Guo, Qianqian, Han, Lili, Zhang, Yamin, Nan, Kejun, Guo, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Libertas Academica 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4525793/
https://www.ncbi.nlm.nih.gov/pubmed/26309408
http://dx.doi.org/10.4137/BCBCR.S30101