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Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E(−/−) mice by activating autophagy

The aim of the present study was to determine whether liraglutide (LRG), a long acting glucagon-like peptide 1 analogue, exerted a protective effect on free fatty acid (FFA)-treated pancreatic β-cells via activating autophagy. INS-1 insulinoma pancreatic islet cell lines were treated with FFA and th...

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Detalles Bibliográficos
Autores principales: WANG, JIA, WU, JIE, WU, HONG, LIU, XINGZHEN, CHEN, YINGJIAN, WU, JIANYING, HU, CHENGJIN, ZOU, DAJIN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526029/
https://www.ncbi.nlm.nih.gov/pubmed/26080706
http://dx.doi.org/10.3892/mmr.2015.3944