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Liraglutide protects pancreatic β-cells against free fatty acids in vitro and affects glucolipid metabolism in apolipoprotein E(−/−) mice by activating autophagy
The aim of the present study was to determine whether liraglutide (LRG), a long acting glucagon-like peptide 1 analogue, exerted a protective effect on free fatty acid (FFA)-treated pancreatic β-cells via activating autophagy. INS-1 insulinoma pancreatic islet cell lines were treated with FFA and th...
Autores principales: | WANG, JIA, WU, JIE, WU, HONG, LIU, XINGZHEN, CHEN, YINGJIAN, WU, JIANYING, HU, CHENGJIN, ZOU, DAJIN |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526029/ https://www.ncbi.nlm.nih.gov/pubmed/26080706 http://dx.doi.org/10.3892/mmr.2015.3944 |
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