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Altered expression of hyperpolarization-activated cyclic nucleotide-gated channels and microRNA-1 and -133 in patients with age-associated atrial fibrillation

Hyperpolarization-activated cyclic nucleotide-gated (HCN) cation channels mediate pacemaker currents in the atrium. The microRNA (miR) families miR-1 and miR-133 regulate the expression of multiple genes involved in myocardial function, including HCN channels. It was hypothesized that age-dependent...

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Detalles Bibliográficos
Autores principales: LI, YAO-DONG, HONG, YI-FAN, YUSUFUAJI, YUEERGULI, TANG, BAO-PENG, ZHOU, XIAN-HUI, XU, GUO-JUN, LI, JIN-XIN, SUN, LIN, ZHANG, JIANG-HUA, XIN, QIANG, XIONG, JIAN, JI, YU-TONG, ZHANG, YU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526032/
https://www.ncbi.nlm.nih.gov/pubmed/26005035
http://dx.doi.org/10.3892/mmr.2015.3831