15-Hydroxyprostaglandin dehydrogenase is upregulated by hydroxychloroquine in rheumatoid arthritis fibroblast-like synoviocytes

15-Hydroxyprostaglandin dehydrogenase (HPGD) is the key enzyme responsible for the metabolic inactivation of prostaglandin E2 (PGE(2)) catabolism. PGE(2) is one of the predominant catabolic factors involved in rheumatoid arthritis (RA). However, the expression and regulation of HPGD in RA fibroblast...

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Detalles Bibliográficos
Autores principales: KIM, HAK-JAE, LEE, SORA, LEE, HAW-YONG, WON, HANSOL, CHANG, SUNG-HAE, NAH, SEONG-SU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526038/
https://www.ncbi.nlm.nih.gov/pubmed/26082314
http://dx.doi.org/10.3892/mmr.2015.3931

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526038/
https://www.ncbi.nlm.nih.gov/pubmed/26082314
http://dx.doi.org/10.3892/mmr.2015.3931

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