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Sanguinarine inhibits angiotensin II-induced apoptosis in H9c2 cardiac cells via restoring reactive oxygen species-mediated decreases in the mitochondrial membrane potential

Cell apoptosis induced by Angiotensin II (Ang II) has a critical role in the development of cardiovascular diseases. The aim of the present study was to investigate whether sanguinarine (SAN), a drug which was proved to have anti-oxidant, anti-proliferative and immune enhancing effects, can abolish...

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Detalles Bibliográficos
Autores principales: LIU, YUAN, JIAO, RONG, MA, ZHEN-GUO, LIU, WEI, WU, QING-QING, YANG, ZHENG, LI, FANG-FANG, YUAN, YUAN, BIAN, ZHOU-YAN, TANG, QI-ZHU
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526052/
https://www.ncbi.nlm.nih.gov/pubmed/26017473
http://dx.doi.org/10.3892/mmr.2015.3841