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Alendronate, a double-edged sword acting in the mevalonate pathway

Aminobisphosphonate aledronate is a compound commonly used clinically for the treatment of osteoporosis and other bone diseases, as a result of it preventing bone resorption. However, in previous years it has also been used to obtain cellular and animal models of a rare genetic disorder termed Meval...

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Detalles Bibliográficos
Autores principales: TRICARICO, PAOLA MAURA, GIRARDELLI, MARTINA, KLEINER, GIULIO, KNOWLES, ALESSANDRA, VALENCIC, ERICA, CROVELLA, SERGIO, MARCUZZI, ANNALISA
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526081/
https://www.ncbi.nlm.nih.gov/pubmed/26096667
http://dx.doi.org/10.3892/mmr.2015.3957