MuRF2 regulates PPARγ1 activity to protect against diabetic cardiomyopathy and enhance weight gain induced by a high fat diet

BACKGROUND: In diabetes mellitus the morbidity and mortality of cardiovascular disease is increased and represents an important independent mechanism by which heart disease is exacerbated. The pathogenesis of diabetic cardiomyopathy involves the enhanced activation of PPAR transcription factors, inc...

Descripción completa

Detalles Bibliográficos
Autores principales: He, Jun, Quintana, Megan T, Sullivan, Jenyth, L Parry, Traci, J Grevengoed, Trisha, Schisler, Jonathan C, Hill, Joseph A, Yates, Cecelia C, Mapanga, Rudo F, Essop, M Faadiel, Stansfield, William E, Bain, James R, Newgard, Christopher B, Muehlbauer, Michael J, Han, Yipin, Clarke, Brian A, Willis, Monte S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Original Investigation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526192/
https://www.ncbi.nlm.nih.gov/pubmed/26242235
http://dx.doi.org/10.1186/s12933-015-0252-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526192/
https://www.ncbi.nlm.nih.gov/pubmed/26242235
http://dx.doi.org/10.1186/s12933-015-0252-x

Ejemplares similares