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Expression of Prostacyclin-Synthase in Human Breast Cancer: Negative Prognostic Factor and Protection against Cell Death In Vitro

Endogenously formed prostacyclin (PGI(2)) and synthetic PGI(2) analogues have recently been shown to regulate cell survival in various cell lines. To elucidate the significance of PGI(2) in human breast cancer, we performed immunohistochemistry to analyze expression of prostacyclin-synthase (PGIS) i...

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Detalles Bibliográficos
Autores principales: Klein, Thomas, Benders, Jens, Roth, Friederike, Baudler, Monika, Siegle, Isabel, Kömhoff, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526217/
https://www.ncbi.nlm.nih.gov/pubmed/26265889
http://dx.doi.org/10.1155/2015/864136