Dynamic Allostery of the Catabolite Activator Protein Revealed by Interatomic Forces

The Catabolite Activator Protein (CAP) is a showcase example for entropic allostery. For full activation and DNA binding, the homodimeric protein requires the binding of two cyclic AMP (cAMP) molecules in an anti-cooperative manner, the source of which appears to be largely of entropic nature accord...

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Detalles Bibliográficos
Autores principales: Louet, Maxime, Seifert, Christian, Hensen, Ulf, Gräter, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526232/
https://www.ncbi.nlm.nih.gov/pubmed/26244893
http://dx.doi.org/10.1371/journal.pcbi.1004358

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526232/
https://www.ncbi.nlm.nih.gov/pubmed/26244893
http://dx.doi.org/10.1371/journal.pcbi.1004358

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