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GATA2(−/−) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment
BACKGROUND: Hematopoiesis is a progressive process collectively controlled by an elaborate network of transcription factors (TFs). Among these TFs, GATA2 has been implicated to be critical for regulating multiple steps of hematopoiesis in mouse models. However, whether similar function of GATA2 is c...
Autores principales: | , , , , , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526303/ https://www.ncbi.nlm.nih.gov/pubmed/26246892 http://dx.doi.org/10.1186/s13619-015-0018-7 |