GATA2(−/−) human ESCs undergo attenuated endothelial to hematopoietic transition and thereafter granulocyte commitment

BACKGROUND: Hematopoiesis is a progressive process collectively controlled by an elaborate network of transcription factors (TFs). Among these TFs, GATA2 has been implicated to be critical for regulating multiple steps of hematopoiesis in mouse models. However, whether similar function of GATA2 is c...

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Detalles Bibliográficos
Autores principales: Huang, Ke, Du, Juan, Ma, Ning, Liu, Jiajun, Wu, Pengfei, Dong, Xiaoya, Meng, Minghui, Wang, Wenqian, Chen, Xin, Shi, Xi, Chen, Qianyu, Yang, Zhongzhou, Chen, Shubin, Zhang, Jian, Li, Yuhang, Li, Wei, Zheng, Yi, Cai, Jinglei, Li, Peng, Sun, Xiaofang, Wang, Jinyong, Pei, Duanqing, Pan, Guangjin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526303/
https://www.ncbi.nlm.nih.gov/pubmed/26246892
http://dx.doi.org/10.1186/s13619-015-0018-7

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