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LMP1 Increases Expression of NADPH Oxidase (NOX) and Its Regulatory Subunit p22 in NP69 Nasopharyngeal Cells and Makes Them Sensitive to a Treatment by a NOX Inhibitor

Oxidative stress is thought to contribute to cancer development. Epstein–Barr virus (EBV) and its encoded oncoprotein, latent membrane protein 1 (LMP1), are closely associated with the transformation of nasopharyngeal carcinoma (NPC) and Burkitt’s lymphoma (BL). In this study, we used LMP1-transform...

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Detalles Bibliográficos
Autores principales: Sun, Jian, Hu, Chongyu, Zhu, Yinghui, Sun, Rui, Fang, Yujing, Fan, Yuhua, Xu, Fei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526464/
https://www.ncbi.nlm.nih.gov/pubmed/26244812
http://dx.doi.org/10.1371/journal.pone.0134896