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Obesity and Hepatic Steatosis Are Associated with Elevated Serum Amyloid Beta in Metabolically Stressed APPswe/PS1dE9 Mice

Diabesity-associated metabolic stresses modulate the development of Alzheimer’s disease (AD). For further insights into the underlying mechanisms, we examine whether the genetic background of APPswe/PS1dE9 at the prodromal stage of AD affects peripheral metabolism in the context of diabesity. We cha...

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Detalles Bibliográficos
Autores principales: Shie, Feng-Shiun, Shiao, Young-Ji, Yeh, Chih-Wen, Lin, Chien-Hung, Tzeng, Tsai-Teng, Hsu, Hao-Chieh, Huang, Fong-Lee, Tsay, Huey-Jen, Liu, Hui-Kang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526466/
https://www.ncbi.nlm.nih.gov/pubmed/26244977
http://dx.doi.org/10.1371/journal.pone.0134531