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Analysis of Conformational B-Cell Epitopes in the Antibody-Antigen Complex Using the Depth Function and the Convex Hull

The prediction of conformational b-cell epitopes plays an important role in immunoinformatics. Several computational methods are proposed on the basis of discrimination determined by the solvent-accessible surface between epitopes and non-epitopes, but the performance of existing methods is far from...

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Detalles Bibliográficos
Autores principales: Zheng, Wei, Ruan, Jishou, Hu, Gang, Wang, Kui, Hanlon, Michelle, Gao, Jianzhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526569/
https://www.ncbi.nlm.nih.gov/pubmed/26244562
http://dx.doi.org/10.1371/journal.pone.0134835