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The Evolutionary Potential of Phenotypic Mutations

Errors in protein synthesis, so-called phenotypic mutations, are orders-of-magnitude more frequent than genetic mutations. Here, we provide direct evidence that alternative protein forms and phenotypic variability derived from translational errors paved the path to genetic, evolutionary adaptations...

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Detalles Bibliográficos
Autores principales: Yanagida, Hayato, Gispan, Ariel, Kadouri, Noam, Rozen, Shelly, Sharon, Michal, Barkai, Naama, Tawfik, Dan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526572/
https://www.ncbi.nlm.nih.gov/pubmed/26244544
http://dx.doi.org/10.1371/journal.pgen.1005445