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The Evolutionary Potential of Phenotypic Mutations
Errors in protein synthesis, so-called phenotypic mutations, are orders-of-magnitude more frequent than genetic mutations. Here, we provide direct evidence that alternative protein forms and phenotypic variability derived from translational errors paved the path to genetic, evolutionary adaptations...
Autores principales: | Yanagida, Hayato, Gispan, Ariel, Kadouri, Noam, Rozen, Shelly, Sharon, Michal, Barkai, Naama, Tawfik, Dan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526572/ https://www.ncbi.nlm.nih.gov/pubmed/26244544 http://dx.doi.org/10.1371/journal.pgen.1005445 |
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