Association of ABCB1 and FLT3 Polymorphisms with Toxicities and Survival in Asian Patients Receiving Sunitinib for Renal Cell Carcinoma

Sunitinib is a tyrosine kinase inhibitor used as first-line treatment for metastatic renal cell carcinoma (mRCC). Asian ethnicity has been previously associated with lower clearance and greater toxicities for sunitinib treatment, relative to Caucasian ethnicity. Research focusing on identifying corr...

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Detalles Bibliográficos
Autores principales: Chu, Ying-Hsia, Li, Huihua, Tan, Hui Shan, Koh, Valerie, Lai, Johnathan, Phyo, Wai Min, Choudhury, Yukti, Kanesvaran, Ravindran, Chau, Noan Minh, Toh, Chee Keong, Ng, Quan Sing, Tan, Puay Hoon, Chowbay, Balram, Tan, Min-Han
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526634/
https://www.ncbi.nlm.nih.gov/pubmed/26244574
http://dx.doi.org/10.1371/journal.pone.0134102

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4526634/
https://www.ncbi.nlm.nih.gov/pubmed/26244574
http://dx.doi.org/10.1371/journal.pone.0134102

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